RESEARCHERS

Estrella Martínez Gómez

GENYO. Centro de Genómica e Investigación Oncológica, Pfizer / Universidad de Granada / Junta de Andalucía - Area de Medicina Genómica

Data

Degree in Biology obtained in the University of Granada (2011). Master in Biomedical Research (2012) and Molecular and Cellular Biology PhD obtained in the University of Navarra (2017). She carried out her doctoral thesis in Microbiology and Parasitology Department by a Ministerio de Educación y Ciencia grant awarded. Postdoctoral secondment at Pharmacology and Pediatrics Department of the University of Malaga (2018-2019). Currently employed by Pzifer Center-University of Granada-Andalusia government center of Genomics and Oncology Research (Genyo) where she works as a Postdoctoral Researcher in the Otology and otoneurology -Genomics of vestibular disorders group.


Province

Granada


Category

BIOLOGY


Departament

GENYO. Centro de Genómica e Investigación Oncológica, Pfizer / Universidad de Granada / Junta de Andalucía - Area de Medicina Genómica


Investigation Group

Otology Neurotology Group CTS495 at the Centre for Genomics and Oncology (Genyo)


Lines of investigation

Meniere disease is a chronic inflammatory disorder of the inner ear characterized by recurrent episodes of vertigo, progressive sensorineural hearing loss and tinnitus. Meniere disease is associated with the endolymph accumulation in the membranous labyrinth.
One of our lines research is based in the idea that pro-inflammatory cytokines releases during a disease crisis could be used as clinical predictor of disease activity and its blocking could be useful to prevent pro-inflammatory response. The results of this proposal may have a significant impact in the management of patients with Meniere disease and may generate a novel personalized therapeutic solution for patients with the elevated levels of pro-inflammatory cytokines.


The most notable result of your research

Our group has identified a genetic biomarker rs4947296 in 14% patients with Meniere disease. By using genotype-conditioned cells, we have found that this variant regulates several genes involve in pro-inflammatory pathways, leading to pro-inflammatory cytokines release


How did you come to science and why are you still here?

Since I was a child, I was curious about science and for discovering new things. During my training, in each step I have been able to getting closer to the scientific world, learning interesting and valuable discoveries that have allowed me to maintain the identical illusion with which I started my vocation.


A scientific desire

To reach more public attendance and to give them the importance of science, research and the researchers of course, so that one day our work will be valued, and be able to be references for future generations.


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